In this paper, we want to check the feasibility and efficacy of LISWT in ED patients
in the frame time between April 2015 and September 2018 we treated for ED 442 pts of which 381 for vasculogenic ED and 61 fo ED following radical prostatectomy. 40 nerve-sparing radical prostatectomy(NSRP) and 21 non-nerve sparing radical prostatectomy(NNSRP) for prostatic cancer, in this group 10 pts received adjuvant radiotherapy for positive surgical margins.
The LISWT protocol we used was 4 sessions (once a week) in one month in vasculogenic ED pts and 6 sessions (once a week) in ED post radical prostatectomy patients with a linear probe at an energy level of 0.09 MJ/cm2. Every time we started a treatment the PSA was <0.03 and there remained afterward. The efficacy of the treatment was validated by the administration of IIEF test and GEQ test.
Results / Discussion
in 442 pts treated with LISWT 276 improved their performances(62%) with or without the help of medications(Pde5 inhibitors or alprostadil) The IIEF was improved by 50% with an average increase from 12 to 18. Of the 381 vasculogenic ED 254 had an improvement in their performance (65%). of these patients, 177 were responders to PDE5 and they got rid of medications. 77 were non-responders to PDE5 or alprostadil and became responders to these drugs.
Of the 40 pts undergone to NSRP 17 improved their status (42%), of the other 21 NNSRP 5 (25%) improved, in this group, 10 pts had adjuvant radio treatment and none improved. We had 5 patients with transitory side effects 3 testis pain 2 penile paresthesias and 1 UTI.
Click for full article: https://doi.org/10.1016/j.jsxm.2019.03.233